I have to say that there is power in vitamins. With gastroparesis comes gastritis and heartburn medicines such as Prevacid, Omeprazole, and Ranidine. I have done the full gambit and have been on them for continuously three years. Lately I have been really negative... every time someone asked me "how are you?" I couldn't say anything positive. Work hasn't been effected, you can't be negative around my students, but everything else has been. Then two days ago I took medicine and wasnt able to sleep all night. You really can't work at my job without sleep so I drank a bottle of 5 hour energy. It didnt give me more energy but it really improved my mood. Suddenly I didn't have anything bad to say, it was great. I looked up proton pump inhibitors and and vitamin B and found that they lead to to vitamin B deficiency. For the last few days I have been taking large amounts of vitamin B12 and have been feeling so much better, its great! If you have GP and have been struggling with your mood, check it out.